Sunday, May 2, 2010

Pancreas, Mucinous Cystic Neoplasm: eMedicine Radiology

Pancreas, Mucinous Cystic Neoplasm: eMedicine Radiology

IPMT is a papillary neoplasm that arises within the MPD or its branches. The tumors hypersecrete mucin, which often leads to duct dilatation and/or chronic obstructive pancreatitis. IPMTs are premalignant and may histologically demonstrate areas ranging from hyperplasia to carcinoma within a single tumor. The tumors generally show intraluminal, longitudinal growth, but it is slow to invade periductal tissues radially and slow to metastasize. IPMTs are most commonly localized to the head of the pancreas, but they may occur at any site along the pancreatic ductal system. Ductal dilatation is often impressive and may mimic MCNs on CT scans.
Intraductal papillary mucinous neoplasm is recognized as predominantly a solid tumor with a central cyst. The cystic variety consists microscopically of cystlike spaces with papillary protrusions.

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